The Sickening Mind: Brain, Behaviour, Immunity and Disease

The Sickening Mind: Brain, Behaviour, Immunity and Disease
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‘A masterpiece of popularization’ Times Literary Supplement‘A fascinating account, based on objective scientific research, of the ways in which mental states affect the individual’s liability to disease… Martin is a highly civilised scientist, who seasons his text with witty parentheses. He also provides many examples from literature, ranging widely from Shakespeare, Goethe and Hardy to Tolstoy, Dostoevsky and Kafka… Interesting, informative and a pleasure to read.’ ANTHONY STORR, Sunday Times‘Excellent’ JON TURNEY, Financial Times‘This most accessible account of a difficult subject blows away some prejudices and pleasingly justifies others… Martin is a biologist whose style is considerate of the layman…and it is a tribute to his own benignly infectious enthusiasm for his subject that his closing thoughts are encouraging… Remarkable.’ ALAN JUDD, Daily Telegraph‘Compelling… Balanced and impressively up to date… The tone of voice, the open-minded but critical intelligence should uplift the quality of the debate… Martin’s lucid account of possible mechanisms of the connections between mental states and personality traits and illnesses is a notable triumph of his book… Excellent.’ RAYMOND TALLIS, Times Literary Supplement

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PAUL MARTIN

The Sickening Mind

Brain, Behaviour, Immunity and Disease


William Collins

An imprint of HarperCollinsPublishers 1 London Bridge Street London SE1 9GF

www.harpercollins.co.uk

This edition published by HarperPress 2005

First published in the UK by HarperCollinsPublishers, 1997

Copyright © Paul Martin, 1997

Paul Martin has asserted the moral right to be identified as the author of this work

The author and publishers are grateful to the following for permission to reproduce material: International Music Publications Limited, for ‘Sex and Drugs and Rock and Roll’ by Ian Drury and Chas Jankel, © 1977 Temple Mill Music Ltd, Warner/Chappell Music Ltd; Hall, J.G., ‘Emotion and immunity’ Lancet, 2, 326–327, © The Lancet Ltd., (1985); extracts from Riceyman Steps by Arnold Bennett by permission A. P. Watt Ltd., on behalf of Mme V. Eldin; extracts from The Man with the Golden Gun by Ian Fleming by permission Glidrose Publications Ltd, © Glidrose Productions Ltd 1965; extract from Three Men in a Boat by Jerome K. Jerome by permission A. P. Watt Ltd., on behalf of The Society of Authors Ltd.; extracts from Down and Out in Paris and London by George Orwell by permission A. M. Heath & Co. Ltd, copyright © The Estate of the late Sonia Brownell Orwell and Martin Secker and Warburg Ltd; extract from Death of a Salesman by Arthur Miller by permission Reed Publishers, © Arthur Miller 1949; extract from ‘Do not go gentle into that good night’ from The Poems by Dylan Thomas by permission David Higham Associates: originally published by J. M. Dent; Thanks also to Harriet Wasserman Literary Agency Inc., for permission to quote from Seize the Day by Saul Bellow; Macmillan General Books, for Jude the Obscure and The Mayor of Casterbridge by Thomas Hardy. Every reasonable effort has been made to contact copyright holders for all the extracts reproduced in this volume. However, it has not been possible to make contact with all copyright holders. The author and publishers would ask, therefore, that any copyright holder who feels a quotation contained herein may contravene their copyright contact HarperCollinsPublishers at the address above.

All rights reserved under International and Pan-American Copyright Conventions. By payment of the required fees, you have been granted the nonexclusive, nontransferable right to access and read the text of this e-book on-screen. No part of this text may be reproduced, transmitted, downloaded, decompiled, reverse engineered, or stored in or introduced into any information storage and retrieval system, in any form or by any means, whether electronic or mechanical, now known or hereinafter invented, without the express written permission of HarperCollins e-books.

HarperCollinsPublishers has made every reasonable effort to ensure that any picture content and written content in this ebook has been included or removed in accordance with the contractual and technological constraints in operation at the time of publication.

Source ISBN: 9780006550228

Ebook Edition © MARCH 2016 ISBN: 9780007383658 Version: 2016-02-25

CONTENTS

COVER

TITLE PAGE

COPYRIGHT

1 The Body of Knowledge

Opening shots

Iraqi SCUDs and Chinese grandmothers

Roundheads and Cavaliers

Some completely fictitious case histories

Invisible worms

Chronic fatigue syndrome

2 Shadows on the Sun

Death, disaster and voodoo

Trouble, strife and sickness

Life events

The mind and the common cold

3 Psyche’s Machine: The Inside Story

The perception of sickness

Bad behaviour

Mind over immune matter

Understanding immunity

Autoimmunity

Measuring immunity

The mind – immunity connections

4 Mind and Immunity

What can the mind do to the immune system?

Bereavement and nuclear disasters

Spaceflight, exams and other nastiness

Does it matter?

What can the immune system do to the mind?

Depression

Immune conditioning

Immune conditioning and disease

Some allergic history revisited

The strange story of the left-handed brain

The wonderful world of herpes

5 The Demon Stress

What is stress?

The biology of stress

Stress, immunity and health

The quality of stress

Control, control and control

The joy of stress

The stress-seekers

6 Other People

Hell is other people? – relationships as stressors

Hell is alone? – the harmful effects of isolation

Michael Henchard’s will

How does it work?

Social relationships and immunity

The lonely future

7 The Wages of Work

The toad work

Who suffers and why?

The scourge of unemployment

8 Sick at Heart

Hearts and minds

The mind in sudden cardiac death and heart disease

Coronary-prone personalities and heart disease

The Type A behaviour pattern

Type A – the evidence

Anger and hostility

How does it work?

Biological reactivity and the Type A person

9 The Mind of the Crab

The mind in cancer

Is there a cancer-prone personality?

Some fictional Type Cs

Psychological influences on survival

How does it work?

10 Encumbered with Remedies

Relax!

Exercise!

Those little pink pills

Psychoneuroimmunology and AIDS

Imagery, miracle cures and other exotica

Kill or cure?

11 Exorcising the Ghost in the Machine

That old mind – body problem

The grip of dualism



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